上海市医学会感染病专科分会

陈小华 主任医师
学会任职: 副主任委员
所属分会: 感染病专科分会
工作单位: 第六人民医院
出诊信息: 点击查看
专业: 传染病学
亚专业: 传染病学
专业主攻方向: 病毒性肝炎免疫机制
主要学术成就、科技奖项、发明创造、著作、重要论文等

1.Ting Yao, Mengjiao Lv, Siyuan Ma, Jinmei Chen, Yi Zhang, Yongsheng Yu, Guoqing Zang, Xiaohua Chen. Ubiquitinated Hepatitis D Antigen-Loaded Microvesicles Induce a Potent Specific Cellular Immune Response to Inhibit HDV Replication in Vivo. Microbiology Spectrum. 2021 Dec 22; 9(3): e0102421. (IF=9.043) 2.Siyuan Ma, Mengjiao Lv, Xiaohua Chen, Guoqing Zang, Zhenghao Tang, Yi Zhang, Weiwei Hu. Avasimibe can cooperate with a DC-targeting and integration-deficient lentivector to induce stronger HBV specific T cytotoxic response by regulating cholesterol metabolism. Antiviral Res. 2023 Jun 29; 216:105662. (IF=7.6) 3.Yi Zhang, Jinmei Chen, Xiaoli Yi, Zhiheng Chen, Ting Yao, Zhenghao Tang, Guoqing Zang, Xuejie Cao, Xiao-Feng Lian, Xiaohua Chen. Evaluation of the metagenomic next-generation sequencing performance in pathogenic detection in patients with spinal infection. Frontiers in Cellular and Infection Microbiology. 2022 Oct 27; 12: 967584. (IF=5.7) 4.Mengjiao Lv, Ting Yao, Yi Zhang, Siyuan Ma, Jinmei Chen, Zhenghao Tang, Guoqing Zang, Xiaohua Chen. Exosomes loading Tapasin enhance T cell immune response by autophagy to inhibit HBV replication. Journal of Medical Virology. 2023 Apr; 95(4): e28746. (IF=12.7) 5.Jingwen Ai, Yi Zhang, Haocheng Zhang, Qiran Zhang, Zhangfan Fu, Ke Lin, Jieyu Song, Yuanhan Zhao, Mingxiang Fan, Hongyu Wang, Yang Zhou, Xiaohua Chen, Chao Qiu, Wenhong Zhang. Safety and immunogenicity of a third-dose homologous BBIBP-CorV boosting vaccination: interim results from a prospective open-label study. Emerg Microbes Infect. 2022 Dec;11(1):639-647. (IF=13.2) 6.Xiaohua Chen, Hongyu Wang, Jingwen Ai, Leer Shen, Lin Ke, Guanmin Yuan, Xiaohua Sheng, Xia Jin, Zhifeng Deng, Jie Xu, Guanzhu Lu, Shujie Chen, Jianpeng Cai, Yi Zhang, Haocheng Zhang, Sen Wang, Wenhong Zhang, Cunyi Fan. Identification of CKD, bedridden history and cancer as higher-risk comorbidities and their impact on prognosis of hospitalized Omicron patients: a multi-center cohort study. Emerg Microbes Infect.2022 Dec;11(1):2501-2509. (IF=13.2) 7.Ting Yao, Jin-Mei Chen, Le-Er Shen, Yong-Sheng Yu, Zheng-Hao Tang, Guo-Qing Zang, Yi Zhang*, Xiao-Hua Chen*. Astragalus polysaccharide alleviated hepatocyte senescence via autophagy pathway. Kaohsiung J Med Sci. 2022 May;38(5):457-468. (IF=3.3) 8.Ting Yao, Weiwei Hu, Jinmei Chen, Leer Shen, Yongsheng Yu, Zhenghao Tang, Guoqing Zang, Yi Zhang, Xiaohua Chen. Collagen XV mediated the epithelial-mesenchymal transition to inhibit hepatocellular carcinoma metastasis. Journal of Gastrointestinal Oncology. 2022 Oct;13(5):2472-2484. (IF=2.1) 9.Ting Yao, Yi Zhang, Mengjiao Lv, Guoqing Zang, Soon Seng Ng*, Xiaohua Chen*. Advances in three-dimensional cell culture for liver preclinical studies. Acta Biochim Biophys Sin. 2021, 53(6), 643–651. 10.Wu S, Zhang Y, Tang Y, Yao T, Lv M, Tang Z, Zang G, Yu Y, Chen X. Molecular epidemiology and clinical characteristics of hepatitis delta virus (HDV) infected patients with elevated transaminases in Shanghai, China. BMC Infect Dis. 2020 Aug 3;20(1):565. (IF=3.09) 11.Xia Hu, Zhenghao Tang, Siyuan Ma, Yongsheng Yu, Xiaohua Chen, Guoqing Zang. Tripartite motif-containing protein 7 regulates hepatocellular carcinoma cell proliferation via the DUSP6/p38 pathway. Biochemical and Biophysical Research Communications. 2019. 511: 889e895. (IF=2.985) 13.Yi Zhang , Jie Chen , Shan-Shan Wu , Meng-Jiao Lv , Yong-Sheng Yu , Zheng-Hao Tang, Xiao-Hua Chen , Guo-Qing Zang. HOXA10 knockdown inhibits proliferation, induces cell cycle arrest and apoptosis in hepatocellular carcinoma cells through HDAC1. Cancer Manag Res. 2019 Jul 26; 11:7065-7076. 14.Parag Mahale, Peter Aka, Xiaohua Chen, Ruth M Pfeiffer, Ping Liu, Sarah Groover, Maimuna Mendy, Ramou Njie, James J Goedert, Gregory D Kirk, Jeffrey S Glenn, Thomas R O'Brien. Hepatitis D virus infection, cirrhosis and hepatocellular carcinoma in The Gambia. J Viral Hepat. 2019;26(6):738-749.