【学术成就】 张浩，男，主任医师，博士研究生导师，现任国家儿童医学中心、上海交通大学医学院附属上海儿童医学中心院长，福建省儿童医院院长, 上海交通大学特聘教授，上海市小儿先天性心脏病研究所所长，上海市儿童罕见病临床医学研究中心主任。长期工作在儿童心血管病外科临床一线，同时聚焦于儿童心血管病外科术式创新、疗效评价、和心肺保护等研究，获得国家自然科学杰出青年基金资助，入选国家万人计划科技创新领军人才，上海市医学领军人才，教育部新世纪优秀人才，曾获树兰医学青年奖、中国青年科技奖和国家科技进步二等奖。以第一或通讯作者于Science Translational Medicine, Nature Communication, Circulation, European Heart Journal, Lancet Child & Adolescent Health, Critical Care Med, ATVB, J Mol Cell Cardiology, J Thoracic Cardiovascular Surgery, Ann Thoracic Surgery等国际权威学术杂志发表论文40余篇。 【科技奖项】 2021 年获得国家科学技术进步二等奖 2021 年入选国家卫生健康突出贡献中青年专家 2019 年入选“上海医学领军人才” 2018 年获得“树兰医学青年奖” 2017 年获得“国家万人计划科技创新领军人才” 2015 年获聘“协和学者特聘教授”并获得“国家杰出青年科学基金” 2014 年获得“中国出生缺陷干预救助基金会”青年学者奖和“东方新星”奖 2013 年获得“中国青年科技奖” 2012 年评为“教育部新世纪优秀人才” 【重要论文】 (1) Huang Y, Lu W, Zeng M, Hu X, Su Z, Liu Y, Liu Z, Yuan J, Li L, Zhang X, Huang L, Hu W, Wang X, Li S*, Zhang H*; Mapping the early life gut microbiome in neonates with critical congenital heart disease: multiomics insights and implications for host metabolic and immunological health. Microbiome. 2022; 10(1):1-22. (通讯作者) (2) YW Liu, YF Zhu, CY Jiang, ZH Su, Y Yan, B Feng, W Mao, YY Zhang, XJ Wang, ZM Xu, H Zhang*; An electrochemical nitric oxide generator for in‑home inhalation therapy in pulmonary artery hypertension. BMC Medicine. 2022; 20(1):481. (通讯作者) (3) Liu Y#, Luo Q#, Su Z#, Xing J, Wu J, Xiang L, Huang Y, Pan H, Wu X, Zhang X, Li J, Yan F, Zhang H*. Suppression of Myocardial Hypoxia-Inducible Factor-1alpha Compromises Metabolic Adaptation and Impairs Cardiac Function in Patients With Cyanotic Congenital Heart Disease During Puberty. Circulation. 2021; 143(23): 2254-72. (通讯作者) (4) Liu X, Hong H, Zhang H, Xu Z, Liu J, Zhang H*. Neonatal surgical outcomes after prenatal diagnosis of complex congenital heart disease: experiences of a perinatal integrated diagnosis and treatment program. World J Pediatrics. 2020.16(5):494-501. (通讯作者) (5) Liu Y#, Xing J#, Li Y, Luo Q, Su Z, Zhang X, Zhang H*. Chronic hypoxia-induced Cirbp hypermethylation attenuates hypothermic cardioprotection via down-regulation of ubiquinone biosynthesis. Sci Transl Med. 2019; 11(489). (通讯作者) (6) Huang Y, Liu YW, Pan HZ, Zhang XL, Li J, Xiang L, Meng J, Wang PH, Yang J, Jing ZC, Zhang H*. Transthoracic Pulmonary Artery Denervation for Pulmonary Arterial Hypertension. Arterioscler Thromb Vasc Biol. 2019; 39(4): 704-18. (通讯作者) (7) Xiang L, Su Z, Liu Y, Zhang X, Li S, Hu S, Zhang H*. Effect of family socioeconomic status on the prognosis of complex congenital heart disease in children: an observational cohort study from China. Lancet Child Adolesc Health. 2018; 2(6): 430-9. (通讯作者) (8) Xing J#, Ying Y#, Mao C#, Liu Y, Wang T, Zhao Q, Zhang X, Yan F, Zhang H*. Hypoxia induces senescence of bone marrow mesenchymal stem cells via altered gut microbiota. Nat Commun. 2018; 9(1): 2020. (通讯作者) (9) Ji TJ#, Feng B#*, Shen J#, Zhang M, Hu YQ, Jiang AX, Zhu DQ, Chen YW, Ji W, Zhang Z, Zhang H*, Li F*. An Avascular Niche Created by Axitinib-Loaded PCL/Collagen Nanofibrous Membrane Stabilized Subcutaneous Chondrogenesis of Mesenchymal Stromal Cells. Adv Sci (Weinh). 2021; 8(20): e2100351. (共同通讯作者)