主要学术成就： 1. 同济大学特聘教授（神经病学） 2. 美国内布拉斯加大学医学中心终身教授 3. 海外高层次人才计划 (长期) 学者 4. 同济大学教育发展基金优秀工作者 5. 国家重大科学研究计划项目(973计划)首席科学家 6. 海外高层次人才计划（第五批, 短期）学者 主要科技奖项： 1. 2008年，美国内布拉斯加州立大学医学中心杰出科学家奖（UNMC Outstanding Scientist Award） 2. 2005年，美国内布拉斯加州立大学医学中心约瑟夫·吉尔摩(青年)科学家奖（UNMC Joseph P. Gilmore Outstanding Investigator Award） 主要承担课题： 在研课题： 1. 课题名称：神经干细胞与胶质细胞释放的外泌体在介导衰老与神经退行性病变中的作用及其分子机制研究 起止日期：2020.01- 2023.12 项目编号：91949204 出资单位：国家自然科学资金委员会（重大研究计划） 资助金额：人民币2050000 2. 课题名称：谷氨酰胺酶C亚型介导的小胶质细胞激活在阿尔兹海默病神经炎症的机制解析 起止日期：2019.01- 2023.12 项目编号：81830037 出资单位：国家自然科学资金委员会（重点项目） 资助金额：人民币2930000 结项课题： 3. 课题名称：诱导性前脑神经细胞体内微环境的组内解析、条件优化和功能模拟 起止日期：2014.01- 2018.08 项目编号：2014CB965001 出资单位：国家重点基础研究发展规划（973计划） 资助金额：人民币15000000 4. 课题名称：中脑多巴胺神经元前体细胞的转分化及其治疗帕金森疾病的研究 起止日期：2014.01- 2017.12 项目编号：81329002 出资单位：国家自然科学资金委员会海外学者合作研究基金 资助金额：人民币2000000 5. 课题名称： 心律失常发生机制研究 起止日期：2013.1- 2015.12 项目编号：81221001 出资单位：国家自然科学资金委员会国家创新研究群体项目 资助金额：人民币6000000 6. 课题名称： 吸入性颗粒物（PM）的界面生物效应研究 起止日期：2012.12- 2016.11 出资单位：中国科学院国际合作研究基金创新团队项目 资助金额：人民币3000000 7. 课题名称：巨噬细胞和神经小胶质细胞在中枢神经退行性疾病中的作用和功能 起止日期：2011.01- 2012.12 项目编号：81028007 出资单位：国家自然科学资金委员会海外学者合作研究基金 资助金额：人民币200000 8. 课题名称："TRAIL and Glutaminase: Neurotoxic Link In HIV Dementia" 起止日期：2001.06-2020.05 项目编号：2R01NS97195 出资单位：DHHS/NIH/NINDS 资助金额：美元7,125,000 9. 课题名称： “SDF-1 and neurogenesis in HIV-1 associated dementia” 起止日期：2008.07-2014.03 项目编号：1R01NS061642 出资单位：DHHS/NIH/NINDS 资助金额：美元1,875,000 10. 课题名称：“HIV-1 Clade Diversity and Macrophage Mediated Neurotoxicity in HIV-1 Dementia” 起止日期：2008.04-2011.03 项目编号：1R21MH083525-01 出资单位：DHHS/NIH/NINDS 资助金额：美元412,500 11. 课题名称：“Regenerative Therapy of Parkinson’s Disease by iPS Cells” 起止日期：2009.07-2011.06 出资单位：NE DHHS – LB606 资助金额：美元150,000 12. 课题名称： "Macrophage Activation, Chemokines, and HIV Dementia " 起止日期：2001.06-2010.04 项目编号：R01NS41858-01 出资单位：DHHS/NIH/NINDS 资助金额：美元3,750,000 13. 课题名称: “Mononuclear phagocytes, immunity and neural progenitor cells” (Project 1); Program project: “Neural immunity in HIV dementia” (each project is equivalent to a R01) 项目编号: 1 P01 NS043985-06A1,P01 NS043985 competitive renewal 起止日期: 5/15/2003-4/30/2013 出资单位：DHHS/NIH/NINDS 资助金额：美元 $3,000,000 Effort:  20% Principal Investigator: H. E. Gendelman; Project 1 leader: J. Zheng 14. 课题名称：“The Effect of Glutaminase Inhibitors in HIV Infection of Macrophages” 起止日期：2004.08-2008.09 出资单位：Guilford Pharmaceuticals 资助金额：美元30,000 15. 课题名称：“Verify a Role for Substance P in HIV Infection of Macrophages” 起止日期：2000.10-2001.04 出资单位：Pfizer, Research & Development Operations 资助金额：美元10,000 16. 课题名称： "Macrophage Activation, Chemokines, and HIV Dementia (supplemental)" 起止日期：2001.10-2002.04 项目编号：R01NS41858-01S1 出资单位：DHHS/NIH/NINDS 资助金额：美元50,000 主要专利： 1.专利名称：“Compositions and Methods for Generating Neural Progenitor Cells” (2011-11-29, in the United States Patent and Trademark Office) 专利申请人: J. Zheng and C. Tian Docket No.： 12032P Serial No.：61/564,636 2.专利名称：一种检测皮层神经元轴突生长导向的方法及其应用（2017-01-18 国内专利） 专利申请人：张敏，赖思强，宋瑷宏，许东升，郑加麟   专利编号：ZL201510199039.5     专利申请单位：上海市第十人民医院 3.专利名称：一种检测原代神经干细胞迁移极化的方法及应用（2017-06-27 国内专利） 专利申请人：张敏，赖思强，郑加麟，许东升，仇丽莎，宋瑷宏   专利编号：ZL201510418616.5     专利申请单位：上海市第十人民医院 4.专利名称：Method and compositions for selective generation of Dopaminergic precursors （国际专利，申报中） 近三年主要论文发表： 学术论文： (* 通讯作者, 总引用次数: 8598; h-index: 56; i10-index: 127) 2022 1.Yuan Pǂ, Li Jǂ, Liu J, Liu H, Gong S, Wang L, Liu J, Li C, Wang Y,Xia X,Zheng JC* (2022). Cognitive dysfunction in patients with pulmonary hypertension. Am J Resp Crit Care. 2022; Accepted. (IF=30.528) 2.Xia X, Wang Y, Qin Y, Zhao S, Zheng JC* (2022). Exosome: a novel neurotransmission modulator or non-canonical neurotransmitter? Ageing Research Reviews. doi:10.1016/j.arr.2022: 74: 101558 3.Fu S, Chen H, Yang W, Xia X*, Zhao S, Xu, X, Ai P, Cai Q, Li X, Wang Y, Zhu J, Zhang B*, Zheng JC* (2022). ROS-targeted Depression Therapy via BSA-incubated Ceria Nanocluster. Nano Letters. 2022; May 18. doi: 10.1021/acs.nanolett.2c01334. Online ahead of print. PMID: 35583518 4.Fu Sǂ, Chen Hǂ, Zhao Sǂ, Yang W, Xia X*, Xu, X, Liang Z, Feng X, Wang Z, Ai P, Ding L, Cai Q, Wang Y, Zhang Y, Zhu J, Zhang B*, Zheng JC* (2022). Insulin-incubated palladium clusters promote recovery after brain injury. J Nanobiotechnology. 2022; (In Press). 5.Ding Lǂ, Wu H, Wang Y, Li Y, Xia X*, Zheng JC* (2022). m6A reader Igf2bp1 regulates the inflammatory responses of microglia by stabilizing Gbp11 and Cp mRNAs. Front. Immunol. 2022; 2022 Apr 29;13:872252. doi: 10.3389/fimmu.2022.872252. eCollection 2022.PMID: 35572575 6.Ma Z, Zheng JC, Li T, Xie Z, Kang L (2022). Janus Kinase Mediates Faster Recovery From Sevoflurane Anesthesia Than Isoflurane Anesthesia in the Migratory Locusts. Front Physiol. 2022 Mar 30;13:806746. doi: 10.3389/fphys.2022.806746. eCollection 2022.PMID: 35431999 7.Gao Gǂ, Li Cǂ, Zhu Jǂ, Sheng S, Liang Z, Fu S, Li X, Sun Y, Wang Y, Feng X, Xia X*, Zheng JC* (2022). Induced neural stem/progenitor cell-derived extracellular vesicles promote recovery post stroke. Clinical and Translational Medicine; (In press).   8.Sun Yǂ, Xia Xǂ, Basnet D, Zheng JC*, Huang J*, Liu J* (2022). Mechanisms of ferroptosis and emerging links to the pathology of neurodegenerative diseases. Front Aging Neurosci. 2022; (In press).                                                                                                                                                                           9.Liu Jǂ, Feng Xǂ, Wang Y, Xia X*, Zheng JC* (2022). Astrocytes: GABAceptive and GABAergic cells in the brain. Front Cell Neurosci. 2022; (In press).                                   10.Liu J, Ding L, Yang X, Liu Y, Wang Y, Li C, Gao G, Zhao S, Sheng S, Xia X*, Zheng JC* (2022). Exosomes mediate APP dysregulation via APP-miR-185-5p axis. Frontiers in Cell and Developmental Biology. doi: 10.3389/fcell.2022.793388 11.Xia X*, Wang Y, Zheng JC* (2022). The microRNA-17~92 family as a key regulator of neurogenesis and potential regenerative therapeutics of neurological disorders. Stem Cell Review & Report. doi: 10.1007/s12015-020-10050-5.     12.Sun X, Zhang M, Lu Z, Zhang Z, Zheng JC, Cheng L, Zeng L, Qian Y, Huang L (2022). Turnover intention and related factors among resident physicians in China under the standardised residency training programme: a cross-sectional survey. 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(2020). Opportunities, risks and challenges in global mental health and population neuroscience: a case of Sino-German cooperation. Eur Arch Psychiatry Clin Neurosci. doi:10.1007/s00406-020-01176-1. 38.Fu S, Wang Y, Xia X*, Zheng JC* (2020). Exosome engineering: current progress in cargo loading and targeted delivery. NanoImpact. doi:10.1016/j.impact.2020.100261. 39.Liu Z , Zheng JC, Tang W. Special Issue on Advanced Diagnosis and Therapy for Major Diseases and Injuries. Nano LIFE. 2020:2002001. doi: 10.1142/S1793984420020018.