上海市医学会脑机融合与神经调控分会

李毅 研究员
学会任职: 副主任委员
工作单位: 中国科学院脑科学与智能技术卓越创新中心
出诊信息: 点击查看
专业: 神经外科
亚专业: 中枢神经损伤,神经再生,神经调控,脑机接口
专业主攻方向: 中枢神经损伤再生、修复与功能重建
主要学术成就、科技奖项、发明创造、著作、重要论文等

李毅,中国科学院脑科学与智能技术卓越创新中心(神经科学研究所)研究员。以第一或通讯作者(含并列)在Nature、Cell、Developmental Cell等国际知名学术期刊上发表了多篇与神经轴突再生、脊髓损伤后修复及功能重建相关的研究工作。2021年加入中国科学院担任中枢神经损伤与功能重建研究组组长。获得国家海外高层次人才引进计划,国家自然科学基金重大研究计划培育项目、国际(地区)合作项目,上海市领军人才(海外)项目资助。 近年发表文章 1.Chengyue Ji#, Yunfan Zhang#, Zeyu Lin#, Yi Li*. (2024) Activation of hypothalamic-pontine-spinal pathway promotes locomotor initiation and functional recovery after spinal cord injury in mice. BioRxiv https://doi.org/10.1101/2024.11.16.621796 ( *通讯作者) 2.Xiaorong Pan#, Yiqing Hu#, Gaowei Lei, Yaxuan, Wei, Jie Li, Tongshu Luan, Yunfan Zhang, Yuanyuan Chu, Yu Feng, Wenrong Zhan, Chunxia Zhao, Frédéric A. Meunier,  Yifan Liu, Yi Li*, and Tong Wang*. (2024) Actomyosin-II Protects Axons from Degeneration Induced by Mild Mechanical Stress. JournalofCellBiology  223(8):e202206046 ( *共同通讯作者) 3.Fei Wang#, Kendra Ruppell#, Songlin Zhou#, Yun Qu , Jiaxin Gong, Ye Shang, Jinglin Wu,Xin Liu,Wenlin Diao,Yi Li*, Yang Xiang*. (2023) Gliotransmission and adenosine signaling promote axon regeneration. Developmental Cell   58(8):660-676.e7.(*共同通讯作者) 4.Faith H. Brennan, Yang Li, Cankun Wang, Anjun Ma, Yi Li, Nicole Pukos, Warren A. Campbell, Kristina G. Witcher, Zhen Guan, Kristina A. Kigerl, Jodie C.E. Hall Jonathan P. Godbout, Andy J. Fischer, Dana M. McTigue, Zhigang He, Qin Ma, and Phillip G. Popovich. (2022) Microglia coordinate cellular interactions during spinal cord repair in mice. Nature Communication 13:4096 5.Li Y#, He X#, Kawaguchi R#, Zhang Y, Wang Q, Monavarfeshani A, Yang Z, Chen B, Shi Z, Meng H, Zhou S, Zhu J, Jacobi A, Swarup V, Popovich P, Geschwind D, He Z*. (2020)Microglia-organized Scar-free spinal cord repair in neonatal mice.Nature587: 613-618 6.Wang J#, He X#, Meng H,Li Y, Dmitriev P, Tian F, Page J, Lu Q, He Z* (2020)Robust Myelination of Regenerated Axons Induced by Combined Manipulations of GPR17 and MicrogliaNeuron108: 43841 7.Boaz Barak#, Zicong Zhang, Yuanyuan Liu, Ariel Nir, Sari S Trangle, Michaela Ennis, Kirsten M Levandowski, Dongqing Wang, Kathleen Quast, Gabriella L Boulting,Li Y,Dashzeveg Bayarsaihan, Zhigang He*, Guoping Feng* (2019)Neuronal deletion of Gtf2i, associated with Williams syndrome, causes behavioral and myelin alterations rescuable by a remyelinating drug;Nature neuroscience22(5): 700 8.Chen B#,Li Y#, Yu B#, Zhang Z, Brommer B, Williams, P.R, Liu Y, Hegarty, S. V, Zhu, S, Zhu, J, Guo, H, Lu, Y, Gu, X*, and He, Z*. (2018)Reactivation of Dormant Relay Pathways in Injured Spinal Cord by KCC2 Manipulations.Cell174(3): 521-535 (#共同第一作者) 9.Liu Y#, Wang X#, Li W#, Zhang Q,Li Y, Zhang Z, Zhu J, Chen B, Williams PR, Zhang Y, Yu B, Gu X, He Z*. (2017)A Sensitized IGF1 Treatment Restores Corticospinal Axon-Dependent Functions.Neuron95(4): 817-833 10.Norsworthy MW#, Bei F, Kawaguchi R, Wang Q, Tran NM,Li Y, Brommer B, Zhang Y, Wang C, Sanes JR, Coppola G, He Z*. (2017)Sox11 Expression Promotes Regeneration of Some Retinal Ganglion Cell Types but Kills Others.Neuron94(6): 1112-1120