主要课题： (1) 国家自然科学基金委员会, 面上项目, 82372186, 液-液相分离诱导肺泡上皮细胞铁自噬-铁死亡及铁蛋白-EV分泌活化肺成纤维细胞促进机械通气相关性肺纤维化的机制, 2024-01-01 至 2027-12-31, 49万元, 在研, 主持 (2) 国家自然科学基金委员会, 面上项目, 82172150, 机械牵张微环境诱导肺泡上皮细胞内质网应激促进DAMP-EV分泌加速机械通气相关性肺纤维化的机制, 2022-01-01 至 2025-12-31, 55万元, 在研, 主持 重要论文： 1、Ri Tang # , Shuya Mei # , Qiaoyi Xu 1, Jinhua Feng 1, Yang Zhou 1, Shunpeng Xing, Zhengyu He*, Yuan Gao*. ASK1-ER stress pathway-mediated fibrotic-EV release contributes to the interaction of alveolar epithelial cells and lung fibroblasts to promote mechanical ventilation-induced pulmonary fibrosis. xp Mol Med. 2022 Dec 6;1-13. 2、Fangfang Sun , Yanwei Lin , Xiaodong Wang , Yuan Gao *, Shuang Ye *. Paxlovid in patients who are immunocompromised and hospitalised with SARS-CoV-2 infection. Lancet Infect Dis. 2022 Sep;22(9):1279. 3、Shuya Mei# , Qiaoyi Xu#, Yue Hu, Ri Tang, Jinhua Feng, Yang Zhou, Shunpeng Xing, Yuan Gao, Zhengyu He. Integrin β3-PKM2 pathway-mediated aerobic glycolysis contributes to mechanical ventilation-induced pulmonary fibrosis. Theranostics. 2022 Aug 15;12(14):6057-6068. 4、 Juan Gao#, Junnan Guo#, Jianxiao Chen#, Chenling Ding, Jiemin Wang, Qian Huang, Ying Jian, Xianyuan Zhao, Min Li,* Yuan Gao,* Chaoyong Yang,* and Wei Wang. d-Amino Acid-Based Metabolic Labeling Enables a Fast Antibiotic Susceptibility Test of Both Isolated Bacteria and Bronchoalveolar Lavage Fluid. Adv Healthc Mater. 2022 Mar;11(6):e2101736. 5、Zhe Li#, Shaojie Qin#, Chen Chen , Shuya Mei, Yulong Yao, Zhanqi Zha, Wen Li*, Yuxiao Deng* and Yuan Gao*. Emerging Trends and Hot Spots of Electrical Impedance Tomography Applications in Clinical Lung Monitoring. Front Med (Lausanne). 2022 Jan 31;8:813640.