近年主持或参加科研项目(课题)及人才计划项目情况: 1. 上海市申康医院发展中心临床科技创新项目,SHDC12021115,基于人工智能(AI)的精子质量分析,2021.12-2024.12,50万,在研,主持 2. 上海市科委西医引导类项目,19411960600,环境化学物对IVF-ET结局影响的研究,2019.03-2022.03,20万,在研,主持 3. 国家自然科学基金重点国际(地区)合作项目,81720108017,雌性生殖干细胞发育与卵巢功能重构机制,2018.1-2022.12,42.68 万,在研,合作方课题负责人 4. 国家重点研发计划,2017YFA0104603-3,人类上皮组织再生机制研究,2017.7-2021.12,684万,已结题,人类子宫内膜的形成机制课题负责人 近年第一作者、通讯作者主要论文 1. Jiaping Pan, Shanshan Liang, Meiyuan Huang, Mei Zhao, Pengcheng Kong, Yiping Liu, Xiaoming Teng, Haixia Wu. Obstetric and neonatal outcomes after frozen-thawed embryos transfer with laser-assisted hatching: a retrospective cohort study. Archives of Gynecology And Obstetrics. 2022 Feb; 305(2): 529-534. doi: 10.1007 /s00404-021-06153- 0. Epub 2021 Aug 14.(IF:2.344)(通2/2) 2. Yi Guo, Zhijuan Cao, Xianting Jiao, Dandan Bai, Yalin Zhang, JingHua, Wenqiang Liu, Xiaoming Teng. Pre-pregnancy exposure to fine particulate matter (PM2.5) increases reactive oxygen species production in oocytes and decrease litter size and weight in mice. Environmental pollution. 2021;268(Pt A):115858. (IF:6.79)(通一) 3. Pengcheng Kong , Yanan Liu , Qianqian Zhu , Mingru Yin , Xiaoming Teng(*).Effect of male age on pregnancy and neonatal outcomes in the first frozen-thawed embryo transfer cycles of IVF/ICSI treatment. Andrology. 2021( May 7) ;9:1540–1548. (IF:3.842) 4. Mei Zhao, Fengli Chi, Tingyu Zhang, Xiaoming Teng, Kunming Li. Human menstrual blood-derived mesenchymal stem cells regulation of the EGF/Ras p21 pathway as a potential therapeutic target for thin endometrium. Annals of Translational Medicine. 2021,9(18): 1476-1489. (IF:3.932)(通2/2) 5. Yi Guo, Dandan Bai, Wenqiang Liu, Yingdong Liu, Yalin Zhang, Xiaochen Kou, Jiayu Chen, Hong Wang, Xiaoming Teng(*), Ji Zuo(*), Shaorong Gao(*).Altered sperm tsRNAs in aged male contribute to anxiety-like behavior in offspring. Ageing cell. First published: 27 August 2021 https://doi.org/10.1111/acel.13466(IF:9.304)(通3/3) 6. Xin Huang, Ling Hong, Yuanyuan Wu, Miaoxin Chen, Pengcheng Kong, Jingling Ruan, Xiaoming Teng, Zhiyun Wei. Raman spectrum of follicular fluid: a potential biomarker for oocyte developmental competence in polycystic ovary syndrome. Frontiers in Cell and Developmental Biology. 2121,11(9):1-13. (IF:6.684)(通3/3) 7. Pengcheng Kong , Mingru Yin , Chuanling Tang , Xiuxian Zhu , Orhan Bukulmez , Miaoxin Chen(*), Xiaoming Teng (*). Effects of Early Cumulus Cell Removal on Treatment Outcomes in Patients Undergoing In Vitro Fertilization: A Retrospective Cohort Study. Front Endocrinol (Lausanne). 2021 May 7;12:669507. doi: 10.3389/fendo.2021.669507. eCollection 2021. (IF:5.555)(通2/2) 8. Wenming Shi, Chunyan Sun, Qiaoyu Chen, Mingming Ye, Jianing Niu, Zhenzhen Meng, Orhan Bukulmez, Miaoxin Chen (*), Xiaoming Teng(*). Association between ambient air pollution and pregnancy outcomes in patients undergoing in vitro fertilization in Shanghai, China: A retrospective cohort study. Environment International.2021.Jan.https://doi.org/10.1016/j.envint.2021.106377 (IF:9.621) 9. Yanping Jia, Kunming Li, Caihong Zheng, Yuanyuan Tang, Dandan Bai, Jiqing Yin, Fengli Chi, Yalin Zhang, Yanhe Li, Zhifen Tu, Yu Wang, Jiaping Pan, Shanshan Liang, Yi Guo, Jingling Ruan, Pengcheng Kong, Bi Wu, Ye Hu, Hong Wang, Wenqiang Liu(*), Xiaoming Teng(*), Shaorong Gao(*). Identification and rescue of a novel TUBB8 mutation that causes the first mitotic division defects and infertility. J Assist Reprod Genet. 2020 Nov 20;47(6):311-319. doi: 10.1016/j.jgg.2020.06.002. Epub 2020 Jun 21.PMID: 32893179(IF:2.829) 10. Dandan Bai, Jin Sun 1, Yanping Jia, Jiqing Yin, Yalin Zhang, Yanhe Li, Rui Gao, Xiling Du, Kunming Li, Jiaming Lin, Zhifen Tu, Yu Wang, Jiaping Pan, Shanshan Liang, Yi Guo, Jingling Ruan, Xiaochen Kou, Yanhong Zhao, Hong Wang, Cizhong Jiang, Fengchao Wang, Xiaoming Teng(*), Wenqiang Liu(*), Shaorong Gao(*).Genome transfer for the prevention of female infertility caused by maternal gene mutation. J Genet Genomics.2020 Jun 20;47(6):311-319. doi: 10.1016/j.jgg.2020.06.002. Epub 2020 Jun 21. (IF:5.065) 11. Miaoxin Chen, Yuanyuan Wu, Xin Huang, Wentao Li, Chunyan Sun, Zhenzhen Meng, Ai Ai, Ling Hong, Chuanling Tang,1 Kunming Li, Yonglun Fu, Zhiqin Chen, Pengcheng Kong, Yi Guo,1 Wenqiang Liu, Ben W Mol, Xiaoming Teng(*). Embryo incubation by time-lapse systems versus conventional incubators in Chinese women with diminished ovarian reserve undergoing IVF/ICSI: a study protocol for a randomized controlled trial. BMJ Open 2020;10:e038657. doi:10.1136/bmjopen-2020-038657(IF:2.496) 12. Miaoxin Chen, Xin Huang, Yiping Liu, Shating Lei, Yuanyuan Wu, Zhiqin Chen, Ling Hong, Xiaoming Teng(*). Systematic oxidative stress is not associated with live birth rate in young non-obese patients with polycystic ovarian syndrome undergoing assisted reproduction cycles: A prospective cohort study. Eur J Obstet Gynecol Reprod Biol. 2020 Oct;253:154-161. doi: 10.1016/j.ejogrb.2020.07.049. Epub 2020 Aug 18. (IF:1.868) 13. Fengli Chi, Mei Zhao, Kunming Li, An-Qi Lin, Yingya Li, Xiaoming Teng(*). DNA methylation status of imprinted H19 and KvDMR1 genes in human placentas after conception using assisted reproductive technology. Annals of Translational Medicine. Vol 8, No 14 (July 2020) (IF:3.297) 14. Xin Huang (*) , Bi Wu , Miaoxin Chen , Ling Hong , Pengcheng Kong , Zhiyun Wei(*) , Xiaoming Teng(*). Depletion of exosomal circLDLR in follicle fluid derepresses miR-1294 function and inhibits estradiol production via CYP19A1 in polycystic ovary syndrome. Aging (Albany NY). (IF:4.831) 2020 Jul 10;12. doi: 10.18632/aging.103602.