上海市医学会手外科专科分会

韩冬 主任医师
学会任职: 副主任委员
所属分会: 手外科专科分会
工作单位: 第九人民医院
出诊信息: 点击查看
专业: 整形外科
亚专业: 手整形
专业主攻方向: 手足四肢整复,疤痕,康复及常见美学手术
主要学术成就、科技奖项、发明创造、著作、重要论文等

2023年获得第13届上海康复医学科技奖(成果类)一等奖。2024年获得中国康复医学会科学技术奖一等奖。 1.Aung ZM, Chen X, Xu C, Sun M, Lin L, Xie L, Xu H, Han D, Chai G.Model Experimental Study of Man-Machine Interactive Robot-Assisted Craniotomy. J Craniofac Surg. 2020 Dec 3. 2.Xu J, Aung ZM, Cheong S, Won T, Zhang R, Xu F, Fan J, Han D.Evaluation of effectiveness of three-dimensional printed ear splint therapy following ear elevation surgery in microtia patients: A randomized controlled trial. J Craniomaxillofac Surg. 2020 Aug;48(8):786-791. 3.Zhao D, Yu Z, Li Y, Wang Y, Li Q, Han D. GelMA combined with sustained release of HUVECs derived exosomes for promoting cutaneous wound healing and facilitating skin regeneration. J Mol Histol. 2020 Jun;51(3):251-263. 4.Zhao D, Jiang W, Wang Y, Wang C, Zhang X, Li Q, Han D.Three-Dimensional-Printed Poly-L-Lactic Acid Scaffolds with Different Pore Sizes Influence Periosteal Distraction Osteogenesis of a Rabbit Skull. Biomed Res Int. 2020 Apr 23;2020:7381391. 5.Du Z, Cui Y, Hao J, Cao Y, Han J, Du C, Han D.New Technique for Correcting Bony Deformity in Racquet Thumb. Ann Plast Surg. 2020 Apr;84(4):390-393. 6.Cao Y, Yang S, Zhao D, Li Y, Cheong SS, Han D, Li Q. Three-dimensional printed multiphasic scaffolds with stratified cell-laden gelatin methacrylate hydrogels for biomimetic tendon-to-bone interface engineering. J Orthop Translat. 2020 Feb 8;23:89-100.(Q1) 7.Zhang H, Mao X, Zhao D, Jiang W, Du Z, Li Q, Jiang C, Han D. Three dimensional printed polylactic acid-hydroxyapatite composite scaffolds for prefabricating vascularized tissue engineered bone: An in vivo bioreactor model. Sci Rep. 2017 Nov 10;7(1):15255.(Q1) 8.Zhao D, Wang Y, Du C, Shan S, Zhang Y, Du Z, Han D. Honokiol Alleviates Hypertrophic Scar by Targeting Transforming Growth Factor-β/Smad2/3 Signaling Pathway. Front Pharmacol. 2017 Apr 19;8:206.(Q1) 9.Zhang H, Mao X, Du Z, Jiang W, Han X, Zhao D, Han D, Li Q.Three dimensional printed macroporous polylactic acid/hydroxyapatite composite scaffolds for promoting bone formation in a critical-size rat calvarial defect model. Sci Technol Adv Mater. 2016 Apr 8;17(1):136-148. (Q1) 10.Zhao D, Wang Y, Han D. Periosteal Distraction Osteogenesis: An Effective Method for Bone Regeneration. Biomed Res Int. 2016;2016:2075317. 11. Zhang H, Du L, Du Z, Jiang H, Han D, Li Q.Association between childhood exposure to single general anesthesia and neurodevelopment: a systematic review and meta-analysis of cohort study.J Anesth. 2015 Oct;29(5):749-57. 12.Han D, Guan X, Wang J, Wei J, Li Q.Rabbit tibial periosteum and saphenous arteriovenous vascular bundle as an in vivo bioreactor to construct vascularized tissue-engineered bone: a feasibility study. Artif Organs. 2014 Feb;38(2):167-74. 13.Han D, Dai K. Prefabrication of a vascularized bone graft with Beta tricalcium phosphate using an in vivo bioreactor. Artif Organs. 2013 Oct;37(10):884-93. 14. Han D, Li J.Repair of bone defect by using vascular bundle implantation combined with Runx II gene-transfected adipose-derived stem cells and a biodegradable matrix. Cell Tissue Res. 2013 Jun;352(3):561-71. 15.Han D, Sun H, Jin Y, Wei J, Li Q. A technique for the non-microsurgical reconstruction of thumb tip amputations. J Plast Reconstr Aesthet Surg. 2013 Jul;66(7):973-7. 16.Han D, Li J, Guan X.Ectopic osteogenesis of hBMP-2 gene-transduced human bone mesenchymal stem cells/BCB. Connect Tissue Res. 2010 Aug;51(4):274-81. 17.Guan XY, Han D.Role of hypercoagulability in steroid-induced femoral head necrosis in rabbits. J Orthop Sci. 2010 May;15(3):365-70. 18.Xu H, Han D, Dong JS, Shen GX, Chai G, Yu ZY, Lang WJ, Ai ST. Rapid prototyped PGA/PLA scaffolds in the reconstruction of mandibular condyle bone defects. Int J Med Robot. 2010 Mar;6(1):66-72. 19.Han D, Hu HT, Jiang H. The subcutaneous pulp flap for fingertip defects. J Hand Surg Am. 2008 Feb;33(2):254-6. 20.Han D, Sun X, Zhang X, Tang T, Dai K. Ectopic osteogenesis by ex vivo gene therapy using beta tricalcium phosphate as a carrier. Connect Tissue Res. 2008;49(5):343-50. 21.Li Y, Yu Z, Zhao D, Han D. Corilagin alleviates hypertrophic scars via inhibiting the transforming growth factor (TGF)-β/Smad signal pathway. Life Sci. 2021 Jul 15;277:119483.(Q1) 22.Yi CAO, Dong HAN. Longitudinal Melanonychia: How to Distinguish a Malignant Condition from a Benign One.Chinese Journal of Plastic and Reconstructive Surgery, 2021, 003(001):P.56-62. 23.Wu S, Wang C, Yao M, Han D, Li Q. Photothermal lipolysis accelerates ECM production via macrophage-derived ALOX15-mediated p38 MAPK activation in fibroblasts. J Biophotonics. 2023 Apr;16(4):e202200321. 24.Xu J, Xue Y, Yu Z, Zhao D, Li X, Fan J, et al. Effect of exoskeleton manipulator on hand function rehabilitation for postburn patients. Disabil Rehabil. 2023 Dec;45(24):4148-55. 25.Zhao D, Wang Y, Yu Z, Wang C, Zhang H, Han D, et al. Co-culture bioprinting of tissue-engineered bone-periosteum biphasic complex for repairing critical-sized skull defects in rabbits. Int J Bioprint. 2023;9(3):698. 26.Du Z, Cui Y, Jiang H, Han D. Reconstruction of polysyndactyly of the fused fifth toe with the fourth toe. J Pediatr Orthop B. 2023 Jan 1;32(1):34-38 27.Zijing Du , Xunhan Qiu, Dong Han, Hao Jiang. Modified Bilhaut-cloquet Procedure for the Reconstruction of Wassel Type III Radial Polydactyly. J Pediatr Orthop 2022 Jul 1;42(6):e636-e640. 28.Yu Z, Li Y, Fu R, Xue Y, Zhao D, Han D. Platycodin D inhibits the proliferation and migration of hypertrophic scar-derived fibroblasts and promotes apoptosis through a caspase-dependent pathway. Arch Dermatol Res. 2023 Jul;315(5):1257-67. (Q1) 29.Yu ZC, Fu R, Li Y, Zhao DY, Jiang H, Han D. The STING inhibitor C-176 attenuates osteoclast-related osteolytic diseases by inhibiting osteoclast differentiation. FASEB J. 2023 Apr;37(4):e22867. (Q1) 30.Xin LI, Dong HAN﹡,Jia XU, Jiajun FAN, Yaxin XUE, Xiaoding GU, Hengxing ZHOU. Current situation and development of facial prosthesis. Chinese Journal of Plastic and Reconstructive Surgery. (accepted) 31.Xue Y, Li Y, Zhang D, Xu W, Ning C, Han D. Calcium Phosphate Silicate Microspheres with Soybean Lecithin as a Sustained-Release Bone Morphogenetic Protein-Delivery System for Bone Tissue Regeneration. ACS Biomater Sci Eng. 2023 May 8;9(5):2596-607.)(Q1) 32.Xue Y, Du Z, Du C, Fan J, Xu J, Li X, et al. Unlocking potential: clinical benefits of enlarging the nail bed explored through continuous W-shaped incisions. J Dermatolog Treat. 2023 Dec;34(1):2241940. 33.Du Z, Cui Y, Jiang H, Han D. Aesthetic outcomes of and anatomic reconstruction for Wassel type IV-D radial polydactyly using a modified Bilhaut-Cloquet procedure. Front Pediatr. 2023;11:1192168. 34.Li X et al., Current situation and development of facial prosthesis, Chinese Journal of Plastic and Reconstructive Surgery, 2023.03.005 35.许佳,韩冬,苏薇洁,等.基于体表压力传感器监测的压力疗法对增生性瘢痕的疗效观察[J].组织工程与重建外科,2023,19(3):229-234 36. Yan Y, Ji Q, Yang J, Yin X, Liu S, Karalkin PA, Reshetov IV, Han D, Li Q, Huang RL. Bioengineering autologous cartilage grafts for functional posterior lamellar eyelid reconstruction: A preliminary study in rabbits. Acta Biomater. 2024 Apr 15;179:106-120. 37.Xue Y, Xu W, Zhao D, Du Z, Jiang H, Lv H, Zhang D, Yu Z, Cao Y, Han D. Biomimetic peroxidase MOF-Fe promotes bone defect repair by inhibiting TfR2 and activating the BMP2 pathway. Biol Direct. 2024 Apr 23;19(1):30. 38.韩冬. 重视手部烧烫伤后瘢痕挛缩畸形的防治[J]. 中华损伤与修复杂志(电子版), 2024, 19(01): 3-7.(述评) 39.李馨, 薛雅心, 樊佳俊, 顾晓丁, 许佳, & 韩冬. 体外冲击波在烧伤爪形手整形术后康复治疗中的应用效果. 中华损伤与修复杂志电子版,2024, 19(01), 12-15. 40.Zhao D, Wang Y, Wang C, Xue Y, Lv H, Xu W, Han D, Sun Y, Li Q. Aberrant expression of messenger and small noncoding RNAomes in aged skin of rats. Mech Ageing Dev. 2025 Feb;223:112022. 41.D. Zhao, J. Xu, X. Li, J.Fan, T. Shen, Z.Du, Y. Cao, H. Jiang, D. Han. Application of 3D Printed Rehabilitation Aids in Hypertrophic Scars, Chinese Journal of Plastic and Reconstructive Surgery, accepted 42.Xu W, Lv H, Xue Y, Shi X, Fu S, Li X, Wang C, Zhao D, Han D. Fraxinellone-mediated targeting of cathepsin B leakage from lysosomes induces ferroptosis in fibroblasts to inhibit hypertrophic scar formation. Biol Direct. 2025 Feb 4;20(1):17. 43.Xu J, Xue Y, Xu W, Li X, Su W, Fan J, Ma Y, Han D. Flexible Pressure Sensors for Optimizing Pressure Garment Therapy in Periarticular Scar Treatment: Preclinical and Clinical Applications. Adv Wound Care (New Rochelle). 2025 Mar 11. 44.Shi X, Xu W, Xue Y, Zhao D, Lv H, Han D, Mao Y, Du Z. Dioscin improves hypertrophic scars by inducing apoptosis and ferroptosis of scar fibroblasts through mitochondrial oxidative stress damage. Eur J Pharmacol. 2025 May 22;1001:177759. 45.Shi Z, Lv H, Wang Y, Zhao D, Han D. A review of strategies for improving the mechanical properties of 3D bioprinted skin grafts. J Mech Behav Biomed Mater. 2025 Oct 6;173:107223. doi: 10.1016/j.jmbbm.2025.107223. Epub ahead of print. PMID: 41066831. 46.Liu Y, Xu W, Zhao D, Li Y, Guo Z, Yuan L, Gao W, Han D, Ye C. Bilayer Hydrogel Scaffold with Directional Micro-Channels and Mechanical Gradient to Promote Osteochondral Repair. Adv Healthc Mater. 2025 Nov 2:e03547. doi: 10.1002/adhm.202503547. Epub ahead of print. PMID: 41178276.