本人连续获7项国家自然科学基金、2项上海市自然科学基金、上海领军人才基金、上海市优秀学科带头人基金、上海交通大学医工交叉重点项目基金等20余项基金资助，总科研经费1300余万元。全国首创“刘丽梅-遗传性糖尿病诊治”专病门诊，建立并应用推广系列MODY精准诊治技术至全国多家医院，精准诊疗超万例患者。成功实现我国MODY诊疗从“经验判断”到“分子分型”、从“盲治”到“精准治疗”的范式转变，引领中国糖尿病精准医学发展。此外，在糖尿病肾病、高血压机制研究方向亦取得突破性进展。迄今为止，在糖尿病、代谢病、高血压、肥胖等顶刊和重要学术杂志发表论著90余篇，彰显出学术与转化的影响力与实力。        荣获2009年“国家科技进步奖”二等奖；2005年“上海市科技进步奖”三等奖；2015年“上海领军人才”、2010年“上海市优秀学科带头人”、2025年吉林大学特殊领军人才A岗、吉林大学第二医院特聘教授。 代表性著作： 1. Zhang Boxiang, Wang Min, Guo Wenlai, Li Jiannan, Zhou Bo, Wang Ze, Wu Siyu, Zhang Hongyan*,  Liu Limei*, Qu Wenrui*. Sustainable zein-based double-layer electrospun dressing: Ca2+-gallic acid co-delivery system for acute bleeding control and wound healing. Materials Today Advances 29 (2026) 100717, Online. (*共同通讯作者） 2. Wang J, Xu B, Wang Y, Liu J, Wang P, Porche R, Kim S, Yang R, Shao XM, Lutfy K, Liu L*, Friedman TC, Jiang M, Liu Y. E-Cigarette Smoke Exposure Elevates Renal MR Expression and Induces BP Elevation. Hypertension. 2025 Sep;82(9):1492-1504. (*共同通讯作者） 3. Zhang J, Zhang R, Liu C, Ge X, Wang Y, Jiang F, Zhuang L, Li T, Zhu Q, Jiang Y, Chen Y, Lu M, Wang Y, Jiang M, Liu Y, Liu L*. Missense mutation of ISL1 (E283D) is associated with the development of type 2 diabetes. Diabetologia. 2024 Aug;67(8):1698-1713.（*通讯作者） 4. Jiang Y, Jiang F, Li M, Wu Q, Xu C, Zhang R, Song M, Wang Y, Wang Y, Chen Y, Zhang J, Ge X, Zhu Q, Zhuang L, Yang D, Lu M, Wang F, Jiang M, Liu X, Liu Y, Liu L*. Identification and management of GCK-MODY complicating pregnancy in Chinese patients with gestational diabetes. Mol Cell Biochem. 2022 May;477(5): 1629 -1643.（*通讯作者） 5. Ying Wang, Jian Wang, Rong Yang, Piwen Wang, Rene Porche, Samuel Kim, Kabirullah Lutfy, Limei Liu*, Theodore C.Friedman, Meisheng Jiang, Yanjun Liu*. Decreased 11β-Hydroxysteroid Dehydrogenase Type 2 Expression in the Kidney May Contribute to Nicotine/Smoking-Induced Blood Pressure Elevation in Mice. Hypertension. 2021. 77:1940–1952. (*通讯作者） 6. Juan Zhang, Yanjun Liu, Ming Li, Xiaoxu Ge, Ying Wang, Xin Huang, Di Yang, Rong Zhang, Yating Chen, Ming Lu, Jun Yin, Mingqiang Song, Yongfeng Wang, Yanzhong Wang, Feng Wang, Meisheng Jiang,Limei Liu*. Identification of Ala2Thr mutation in insulin gene from a Chinese MODY10 family. Mol Cell Biochem. 2020. 470(1-2):77-86 .（*通讯作者） 7. Limei Liu*, Yanjun Liu, Xiaoxu Ge, Xipeng Liu, Chen Chen, Yanzhong Wang, Juan Zhang, Yating Chen, Rong Zhang, Weijing Zhao , Yanyan Jiang, Di Yang, Taishan Zheng, Meisheng Jiang. Insights into  pathogenesis  of  five  novel  GCK  mutations  identified  in  Chinese  MODY patients. Metabolism. 2018. 89: 8–17 .（*第一兼通讯作者） 8.  Limei Liu*, Kazuaki Nagashima, Takao Yasuda, Yanjun Liu, Hai-rong Hu, Guang He, Bo Feng, Mingming Zhao, Langen Zhuang, Taishan Zheng, Theodore C. Friedman, Kunsan Xiang. Mutations in KCNJ11 are associated with the development of autosomal dominant, early-onset type 2 diabetes. Diabetologia. 2013. 56(12):2609-18 .（*第一兼通讯作者） 9. Limei Liu*, Taishan Zheng, Feng Wang, Niansong Wang, Yanyan Song, Ming Li, Lifang Li, Jiamei Jiang, Weijing Zhao. Pro12Ala polymorphism in the PPARG gene contributes to the development of diabetic nephropathy in Chinese type 2 diabetes. Diabetes Care. 2010.33:144 – 149 . （*第一兼通讯作者） 著作：参编《个体化用药遗传咨询指南》（2022版）；主编专著《糖尿病肾病》；参编专著《特殊类型糖尿病》等。