个人以第一完成人承担国家自然科学基金3项、第2完成人承担国家自然科学基金2项、其他各级科研项目10余项。出版专著多部，发表学术论著30余篇，学术专著4部，科普专著1部，专利3项。 主要科研项目： 81371979 国自然面上项目CXCL13FAK 对激素性股骨头坏死中MSCs 转归的调控机制研究（第一完成人） 81972055 国自然面上项目 重置生物钟逆转MSCs早衰改善OA软骨下骨重塑的机制研究（第一完成人） 30700853 国自然青年项目 基于成骨微环境响应的种子细胞捕获机制的建立（第一完成人） 22ZR1455800 上海市自然基金 USP10调节胞内应激颗粒G3BP1泛素化水平对骨关节炎的影响机制研究 （项目负责人） 2024ZDXK0031 上海市卫生健康系统重点学科 骨外科学（项目负责人） 24010702800 上海市科学技术委员会科技计划项目 依托AI疾病预测模型与基层医疗网络构建边境山区膝骨关节炎 （项目负责人） PWRl2021-01 浦东新区卫生系统领先人才项目 SGs调控MSCs衰老修复OA软骨下骨损伤的机制研究 （项目负责人） PWYgy2018-09 浦东新区高原学科建设项目 创伤骨科 （项目负责人） PWYgy2021-04 浦东新区高原学科建设项目 创伤骨科 （项目负责人） 2024-PWXZ-14 浦东新区公立医院临床医学新质专科建设项目 创伤骨科 （项目负责人） PW2021D-08 浦东新区卫健委联合攻关项目髌股关节OA智能化精准诊断体系建设的探索性研究 （项目负责人） PWKP2021B-09 浦东卫健委科普展示活动“防老先防腿”—老年性膝骨关节炎的科学认知与行为矫正 （项目负责人） 主要学术论文： 1.Zhanrong Kang, Dejian Li, Chaoqin Shu, Jianhang Du, Bin Yu, Zhi Qian, Zeyuan Zhong, Xu Zhang, Baoqing Yu, Qikai Huang, Jianming Huang, Yufang Zhu, Chengqing Yi, Huifeng Ding. Polydopamine Coating-Mediated Immobilization of BMP-2 on Polyethylene Terephthalate-Based Artificial Ligaments for Enhanced Bioactivity. Frontiers in Bioengineering and Biotechnology. 2021 Nov 16;9:749221. ISSN:2296-4185. Q3. IF=5.89. 2.Dejian Li, Kai Zhao, Ziwen Zhao, Bo Jiang, Xianxu Gong, Yan Zhang, Yingqi Guo, Han Xiao, Ye Wang, Hui Liu, Chengqing Yi, Wenguang Gu. High Expression MicroRNA-206 Inhibits the Growth of Tumor Cells in Human Malignant Fibrous Histiocytoma. Frontiers in Cell and Developmental Biology. 2021 Nov 25;9:751833. ISSN:2296-634X. Q2. IF=6.684. 3.Juan Liu, Xin Qi, Xiao-Hong Wang, Hong-Sheng Miao, Zi-Chao Xue, Le-Le Zhang, San-Hu Zhao, Liang-Hao Wu, Guo-Yi Gao, Mei-Qing Lou, Cheng-Qing Yi. Downregulation of the LncRNA MEG3 Promotes Osteogenic Differentiation of BMSCs and Bone Repairing by Activating Wnt/β-Catenin Signaling Pathway. Journal of Clinical Medicine. 2022 Jan 13;11(2):395. ISSN:2077-0383. Q3. IF=4.964. 4.Chongjing Zhang, Zeyuan Zhong, Weicong Sang, Farnaz Ghorbani, Behafarid Ghalandari, Marjan Mohamadali, Shiva Irani, Zhi Qian, Chengqing Yi, Baoqing Yu. The Dibenzyl Isoquinoline Alkaloid Berbamine Ameliorates Osteoporosis by Inhibiting Bone Resorption. Frontiers in Endocrinology (Lausanne). 2022 May 18;13:885507. ISSN:1664-2392. Q3. IF=6.055. 5.Tao Lv, Xiuzhang Ye, Zhen Jian, Zeyuan Zhong, Chongjing Zhang, Chengqing Yi, Baoqing Yu. Oxyresveratrol Reduces the Migration of Human Osteosarcoma Cell U2OS via  Attenuating STAT3 Activation. Natural Product Communications. 2022, Jun 17(6):1-7. ISSN:1934-578X. Q4. IF=1.496. 6.Shi Shi, Jing Chen, Xiwei Wang, Mingshu Xiao, Arun Richard Chandrasekaran, Li Li, Chengqing Yi, Hao Pei. Biointerface Engineering with Nucleic Acid Materials for Biosensing Applications. Advanced Functional Materials. 2022, 32;37:202201069. ISSN:1616-301X. Q1. IF=19.924. 7.Jianhang Du, Ying Zhou, Xiaogang Bao, Zhanrong Kang, Jianming Huang, Guohua Xu, Chengqing Yi, Dejian Li. Surface polydopamine modification of bone defect repair materials: Characteristics and applications. Frontiers in Bioengineering and Biotechnology. 2022 Jul 22;10:974533. ISSN:2296-4185. Q3. IF=6.064. 8.Hanru Ren, Lianghao Wu, Xu Zhang, Zheng Jian, Chengqing Yi. Morphological Analysis of Fractures of the Proximal Humerus by the Fracture Mapping Technique. Orthopaedic Surgery. 2023 Aug;15(8):2042-2051. ISSN:1757-744X. Q3. IF=1.8. 9.Dejian Li, Hanru Ren, Xu Zhang, Rongguang Ao, Chengqing Yi, Baoqing Yu. Finite Element Analysis of Channel Screw and Conventional Plate Technique in Tile B2 Pelvic Fracture. Journal of Personalized Medicine. 2023 Mar 10;13(3):506. ISSN:2075-4426. Q4. IF=3. 10.Zeyuan Zhong, Chongjing Zhang, Shuo Ni, Miao Ma, Xiaomeng Zhang, Weicong Sang, Tao Lv, Zhi Qian, Chengqing Yi, Baoqing Yu. NFATc1-mediated expression of SLC7A11 drives sensitivity to TXNRD1 inhibitors in osteoclast precursors. Redox Biology. 2023 Jul;63:102711. ISSN:2213-2317. Q1. IF=10.7. 11.Hanru Ren, Lianghao Wu, Xu Zhang, Zhen Jian, Chengqing Yi. The effect of integrity of lesser tuberosity-medial calcar on postoperative outcome in the proximal humeral fracture. Journal of Orthopaedic Surgery and Research. 2023 May 16;18(1):363. ISSN:1749-799X. Q3. IF=2.8. 12.Dejian Li, Jiawen He, Jianhua Zhou, Chengqing Yi, Qikai Huang. Fixation of Calcaneal Tuberosity Beavis II Fracture in Elderly Patients Using Locking Plate Combined with Tension Screw. Biomedical Engineering Communications. 2023，2(1)：2. 2023-09-07. ISSN:2815-9063. Q4. IF=0.6. 13.Shi Shi, Lele Zhang, Qi Wang, Qian Wang, Dejian Li, Wei Sun, Chengqing Yi. Targeting Cartilage miR-195/497 Cluster for Osteoarthritis Treatment Regulates the Circadian Clock. Gerontology. 2024;70(1):59-75. ISSN:0304-324X. Q2. IF=3.1. 14.Hanru Ren, Xu Zhang, Yakun Liang, Chengqing Yi, Dejian Li. Morphological analysis of posterior-medial intertrochanteric fracture patterns using fracture-mapping technique. Frontiers in Bioengineering and Biotechnology. 2023 Nov 9:11:1275204. ISSN:2296-4185. Q2. IF=4.3. 15.Lianghao Wu, Xu Zhang, Chengqing Yi, Hanru Ren. CD146-positive adipose-derived stem cells subpopulation enriched by albumin magnetic sphere ameliorates knee osteoarthritis pain and promotes cartilage repair. Journal of Orthopaedic Surgery and Research. 2023 Dec 15;18(1):969. ISSN:1749-799X. Q3. IF=2.8. 16.Hanru Ren, Lele Zhang, Xu Zhang, Chengqing Yi, Lianghao Wu. Specific lipid magnetic sphere sorted CD146-positive bone marrow mesenchymal stem cells can better promote articular cartilage damage repair. BMC Musculoskeletal Disorders. 2024 Apr 1;25(1):253. ISSN:1471-2474. Q3. IF=2.2. 17.Qi Wang, Beijie Qi, Shi Shi, Weihao Jiang, Dejian Li, Xinhua Jiang, Chengqing Yi. Melatonin Alleviates Osteoarthritis by Regulating NADPH Oxidase 4-Induced Ferroptosis and Mitigating Mitochondrial Dysfunction. Journal of Pineal Research. 2024 Sep;76(6):e12992. ISSN:0742-3071. Q1. IF=8.3. 18.Zhen Jian, Xinhua Jiang, Dejian Li, Jianhua Zhou, Baoqing Yu, Chengqing Yi. Finite element analysis of a novel anatomical plate in posterolateral plateau fractures. Frontiers in Surgery. 2024 Jul 15;11:1346462. ISSN:2296-875X. Q4. IF=1.6. 19.Ziwen Zhao, Chenxu Wang, Aiguo Liu, Ning Bai, Bo Jiang, Yuanfu Mao, Ting Ying, Daming Dong, Chengqing Yi, Dejian Li. Multiple applications of metal-organic frameworks (MOFs) in the treatment of orthopedic diseases. Frontiers in Bioengineering and Biotechnology. 2024 Sep 4;12:1448010. ISSN:2296-4185. Q3. IF=4.3. 20.Aiguo Liu, Chenxu Wang, Shuang Deng, Sitong Zhang, Ziwen Zhao, Han Xiao, Ting Ying, Chengqing Yi, Dejian Li. Application of Light-Responsive Nanomaterials in Bone Tissue Engineering. Pharmaceutics. 2025 Jan 13;17(1):98. ISSN:1999-4923. Q3. IF=4.9. 21.Chenxu Wang, Aiguo Liu, Ziwen Zhao, Ting Ying, Shuang Deng, Zhen Jian, Xu Zhang, Chengqing Yi, Dejian Li. Application and progress of 3D printed biomaterials in osteoporosis. Frontiers in Bioengineering and Biotechnology. 2025 Feb 4;13:1541746. ISSN:2296-4185. Q3. IF=4.3. 22.Aiguo Liu, Ting Ying, Shuang Deng, Chenxu Wang, Ziwen Zhao, Sitong Zhang, Han Xiao, Chengqing Yi, Dejian Li. Relationship between albumin-corrected anion gap and lumbar spine bone mineral density: a cross-sectional study. Frontiers in Aging. 2025 Feb 11;6:1511294. ISSN:2296-9144. Q4. IF=3.3. 23.Aiguo Liu, Chenxu Wang, Ziwen Zhao, Rui Zhu, Shuang Deng, Sitong Zhang, Farnaz Ghorbani, Ting Ying, Chengqing Yi, Dejian Li. Progress of porous tantalum surface-modified biomaterial coatings in bone tissue engineering. Journal of Materials Science: Materials in Medicine. 2025 Mar 5;36(1):26. ISSN:0957-4530. Q3. IF=4.2. 24.Jianhang Du, Xiaogang Bao, Jing Wen, Chen Tang, Chenxu Wang, Changgui Shi, Chengqing Yi, Guohua Xu, Dejian Li. SrCO3@PCL/PDA composite scaffold promote osteoporotic bone regeneration through immune regulation. Composites Part B-Engineering. 2025 Mar 298:112406. ISSN:1359-8368. Q1. IF=12.7. 25.Beijie Qi, Qi Wang, Shi Shi, Qian Wang, Weihao Jiang, Chenxu Wang, Dejian Li, Yaying Sun, Chengqing Yi. Si-ITGA6-Loaded Liposomes Inhibit Capsule Fibrosis via the FAK/PI3K/Akt Signaling Pathway in Adhesive Capsulitis of Shoulder. International Journal of Nanomedicine. 2025 Apr 5;20:4183-4200. ISSN:1176-7816. Q2. IF=6.7. 26.Beijie Qi, Zhixin Che, Han Lin, Yaying Sun, Chengqing Yi, Jiwu Chen. Antioxidant RuCo nanosheet attenuates capsule fibrosis in adhesive capsulitis of shoulder by p38 MAPK signaling pathway inhibition, Materials Today Bio. 2025:20 4188-4200. ISSN:2590-0064.Q1. IF=10.2. 学术专著： 主译《实用髋、膝关节置换术：要点与技巧》 主译《前交叉韧带翻修手术学》 副主译《关节镜外科学》 副主译《骨科、运动医学与康复中的本体感觉》 科普专著： 《慢病早治36计》 所获专利： 发明专利：用于肩关节镜手术的球囊撑开装置（第二） 实用新型专利：一种用于骨盆前环的微创复位固定器（第一） 实用新型专利：一种用于骨盆骨折的微创复位器（第二）